Interaction between Amino Propeptides of Type XI Procollagen α1 Chains

Interaction Between Amino Propeptides of Type XI Procollagen 1 Chains

Collagen Type XI α1 Chain Amino Propeptide Structural Model and Glycosaminoglycan Interactions in Silico

Modeling of the collagen 1(XI) amino propeptide (NPP) domain was performed to better understand how dimerization and glycosaminoglycan binding are coordinated. The program MODELLER was used to generate a homology model of collagen 1(XI) NPP domain based on the crystal structure of the closely related NC4 domain of collagen 1 (IX) (PDB:2UUR) to a root mean square deviation (rmsd) of 0.785 Å r...

Identification of the molecular recognition sequence which determines the type-specific assembly of procollagen.

A key question relating to procollagen biosynthesis is the way in which closely related procollagen chains discriminate between each other to assemble in a type-specific manner. Intracellular assembly of procollagen occurs via an initial interaction between the C-propeptides followed by vectorial propagation of the triple-helical domain in the C to N direction. Recognition signals within the C-...

the investigation of the relationship between type a and type b personalities and quality of translation

چکیده ندارد.

Characterization of type III procollagen from chick embryo blood vessels.

The precursors of collagen types I and III were extracted from radioactively labeled chick embryo blood vessels. Procollagen III was found to consist of three identical proa III chains, each containing a large amino and a large carboxyl propeptide. Interchain disulfide bridges occur at three locations: between the amino propeptides, the carboxyl propeptides, and within the vertebrate collagenas...